10-Thiastearic Acid

Heteroatom-substituted fatty acids have been observed to modulate the extension and desaturating of fatty acids, and to influence their distribution within phospholipids pools. 10-Thiastearic acid inhibits desaturation of radiolabeled stearate to oleate in rat hepatocytes and hepatoma cells by more than 80% at a concentration of 25 µM. This activity is associated with a hypolipidemic effect, making this 10-thiastearic acid a useful tool for evaluating new anti-obesity therapeutics.Formal Name: 9-(octylthio)-nonanoic acid. CAS Number: 105099-89-6. Molecular Formula: C17H34O2S. Formula Weight: 302.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): .15 mg/ml. SMILES: CCCCCCCCSCCCCCCCCC(O)=O. InChi Code: InChI=1S/C17H34O2S/c1-2-3-4-5-9-12-15-20-16-13-10-7-6-8-11-14-17(18)19/h2-16H2,1H3,(H,18,19). InChi Key: OMIBNTWPNMKIGZ-UHFFFAOYSA-N.