1,2-bis(heptanoylthio) Glycerophosphocholine

1,2-bis(heptanoylthio) Glycerophosphocholine (Diheptanoyl Thio-PC) is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH). Interaction of this compound with a PLA2 results in cleavage of the sn-2 fatty acid generating a free thiol on the lysophospholipid. This free thiol can be detected using chromogenic substrates such as DTNB (Ellman's reagent) and DTP.Formal Name: (S)-4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxoheptyl)thio]-3,5-dioxa-9-thia-4-phosphahexadecan-1-aminium. CAS Number: 89019-63-6. Synonyms: Diheptanoyl Thio-PC, 1,2-bis(Heptanoylthio)-1,2-dideoxy-sn-glycero-3-phosphorylcholine. Molecular Formula: C22H44NO6PS2. Formula Weight: 513.7. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, Ethanol: 25 mg/ml, PBS, pH 7.2: 62 µg/ml. SMILES: CCCCCCC(SC[C@@H](SC(CCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O)=O. InChi Code: InChI=1S/C22H44NO6PS2/c1-6-8-10-12-14-21(24)31-19-20(32-22(25)15-13-11-9-7-2)18-29-30(26,27)28-17-16-23(3,4)5/h20H,6-19H2,1-5H3/t20-/m0/s1. InChi Key: LFFIJRJGKBSELO-FQEVSTJZSA-N.