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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABD-21241 | 1 mg | - |
3 - 8 business days* |
369.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Molecular weight: 710.72. Excitation (nm): 643. Emission (nm): 660. Lysosomes are membrane-bound... more
Product information "Protonex(TM) Lyso-Red 670"
Molecular weight: 710.72. Excitation (nm): 643. Emission (nm): 660. Lysosomes are membrane-bound organelles containing acid hydrolases that break down biomolecules in an acidic environment (pH 4.5-4.8). They play critical roles in cellular processes by eliminating waste and debris, facilitating autophagy for organelle recycling, and mediating digestion through endocytosis and phagocytosis. Lysosomes aid cellular metabolism by converting complex molecules into usable forms and contribute to cell signaling, influencing growth, differentiation, and responses to signals. Dysfunctional lysosomes are associated with various diseases called lysosomal storage disorders, where the accumulation of undigested substances within lysosomes leads to cellular damage and systemic health issues. Notably, lysosomal dysfunction has been implicated in neurodegenerative diseases, cancer, and other disorders. Protonex(TM) Lyso-Red 670 is a cell-permeable, far-red fluorescent probe that selectively stains and visualizes acidic organelles within live cells, notably lysosomes. It remains quiescent or weakly fluorescent under alkaline pH conditions, exhibiting significant fluorescence enhancement as acidity increases. This property enables researchers to trace lysosomal dynamics (e.g., trafficking, fusion, fission, autophagy) in real-time via fluorescence microscopy techniques. Protonex(TM) Lyso-Red 670 has an excitation and emission maximum of 640 and 680 nm, respectively, and can be efficiently excited using a Cy5 filter.
Supplier: | AAT Bioquest |
Supplier-Nr: | 21241 |
Properties
Application: | Lysosomal dynamics (trafficking, fusion, fission, autophagy) tracing, real-time fluorescence micros. |
MW: | 710.72 D |
Database Information
Handling & Safety
Storage: | -20°C (protect from light) |
Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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