Zerumbone

Zerumbone is a natural monocyclic sesquiterpene first isolated from rhizomes of the wild ginger Z. zerumbet. It potently inhibits the activation of Epstein-Barr virus by phorbol esters (IC50 = 140 nM). Zerumbone inhibits Sonic hedgehog signaling and induces apoptosis in cancer cell lines. It has also been shown to have anti-oxidant and anti-inflammatory activities, contributing to immunomodulatory and hepatoprotective effects.Formal Name: (2E,6E)-2,6,9,9-tetramethyl-2,6,10E-cycloundecatrien-1-one. CAS Number: 471-05-6. Molecular Formula: C15H22O. Formula Weight: 218.3. Purity: >95%. Formulation: (Request formulation change), Solid white crystals or powder. Solubility: DMSO: soluble, Ethanol: soluble. SMILES: CC1(C)C/C=C(C)/CC/C=C(C)\C(/C=C/1)=O. InChi Code: InChI=1S/C15H22O/c1-12-6-5-7-13(2)14(16)9-11-15(3,4)10-8-12/h7-9,11H,5-6,10H2,1-4H3/b11-9+,12-8+,13-7-. InChi Key: GIHNTRQPEMKFKO-WHILTJODSA-N. Origin: Plant/Curcuma zerumbet.