Wortmannin
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and... more
Product information "Wortmannin"
Description: Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible. Wortmannin is also an inhibitor of PlK1 and PlK3 (IC50=5.8/48 nM) that blocks autophagy. Target: Serine/threonin kinase, PI3K, ATM/ATR, Autophagy, Antibiotic, PLK, DNA-PK. Smiles: COCC1OC(=O)c2coc3c2C1(C)C1=C(C2CCC(=O)C2(C)CC1OC(C)=O)C3=O. References: Akter R, et al. Wortmannin induces MCF-7 breast cancer cell death via the apoptotic pathway, involving chromatin condensation, generation of reactive oxygen species, and membrane blebbing. Breast Cancer (Dove Med Press). 2012 Jul 13,4:103-13.
| Keywords: | KY-12420, SL-2052 |
| Supplier: | TargetMol |
| Supplier-Nr: | T6283 |
Properties
| Application: | PI3 kinase inhibitor, Adipogenesis inhibitor, Angiogenesis inhibitor |
| MW: | 428.43 D |
| Formula: | C23H24O8 |
Database Information
| CAS : | 19545-26-7| Matching products |
| KEGG ID : | K00922 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H300, H310, H330 |
| P Phrases: | P260, P262, P264, P270, P271, P280, P284, P301+310, P302+352, P304+340, P310, P320, P321, P330, P361+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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