W-54011

Item number	Size	Delivery time	Price
TGM-T17250-1mg	1 mg	7 - 10 business days*	77.00€
TGM-T17250-5mg	5 mg	7 - 10 business days*	128.00€
TGM-T17250-1mL	1 ml	7 - 10 business days*	166.00€
TGM-T17250-10mg	10 mg	7 - 10 business days*	195.00€
TGM-T17250-25mg	25 mg	7 - 10 business days*	352.00€
TGM-T17250-50mg	50 mg	7 - 10 business days*	544.00€
TGM-T17250-100mg	100 mg	7 - 10 business days*	785.00€

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Description: W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the... more

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Product information "W-54011"

Description: W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki = 2.2 nM). W-54011 inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and generation of ROS in human neutrophils (IC50s = 3.1 nM, 2.7 nM, and 1.6 nM, respectively). Target: ROS, Complement System. Smiles: Cl.COc1ccc2CCCC(C(=O)N(Cc3ccc(cc3)N(C)C)c3ccc(cc3)C(C)C)c2c1. References: Sumichika H, et al. Identification of a potent and orally active non-peptide C5a receptor antagonist. J Biol Chem. 2002 Dec 20,277(51):49403-49407.

Supplier:	TargetMol
Supplier-Nr:	T17250

Properties

Application:	C5a Receptor Antagonist
MW:	493.08 D
Formula:	C30H37ClN2O2

Database Information

CAS :	405098-33-1\| Matching products
KEGG ID :	K04010 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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