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Description: VU534 is a NAPE-PLD agonist with an EC50 of 0.30 µM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 µM for sEH.VU534 is used in diseases related to cardiometabolism. Target: Phospholipase, FAAH, Epoxide Hydrolase. Smiles: CC1=CC2=C(SC(NC(=O)C3CCN(CC3)S(=O)(=O)C3=CC=C(F)C=C3)=N2)C(C)=C1. References: Zarrow JE, et al. Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages. bioRxiv [Preprint]. 2023 Feb 28:2023.01.25.525554.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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