VU0422288

VU0422288
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T29135-5mg 5 mg

7 - 10 business days*

72.00€
TGM-T29135-10mg 10 mg

7 - 10 business days*

124.00€
TGM-T29135-25mg 25 mg

7 - 10 business days*

246.00€
TGM-T29135-50mg 50 mg

7 - 10 business days*

395.00€
TGM-T29135-100mg 100 mg

7 - 10 business days*

658.00€
TGM-T29135-500mg 500 mg

7 - 10 business days*

1,330.00€
 
Description: VU0422288 (ML396) is a potent orthosteric modulator of type III mGlu receptors... more
Product information "VU0422288"
Description: VU0422288 (ML396) is a potent orthosteric modulator of type III mGlu receptors (mGlus).VU0422288 shows inhibition of mGluR4, mGluR7, and mGluR8 in a calcium mobilization assay.VU0422288 can be used to study Rett syndrome (RTT). Target: GluR. Smiles: Clc1ccc(Oc2ccc(NC(=O)c3ccccn3)cc2Cl)nc1. References: Gogliotti RG, et al. mGlu7 potentiation rescues cognitive, social, and respiratory phenotypes in a mouse model of Rett syndrome. Sci Transl Med. 2017 Aug 16,9(403):eaai7459.
Keywords: ML 396, VU 0422288, VU-0422288, ML-396, ML396
Supplier: TargetMol
Supplier-Nr: T29135

Properties

Application: Group III metabotropic glutamate receptor positive allosteric modulator
MW: 360.19 D
Formula: C17H11Cl2N3O2

Database Information

CAS : 1630936-95-6| Matching products
KEGG ID : K04607 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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