VU0364439

VU0364439 is a positive allosteric modulator of metabotropic glutamate receptor 4 (mGluR4) that potentiates glutamate responses in CHO cells expressing recombinant human mGluR4 (EC50 = 19.8 nM).Formal Name: N-[3-chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide. CAS Number: 1246086-78-1. Molecular Formula: C18H13Cl2N3O3S. Formula Weight: 422.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 3 mg/ml, DMSO: 3 mg/ml, DMSO:PBS (pH 7.2) (1:5): 0.16 mg/ml. lambdamax: 280 nm. SMILES: O=C(C1=NC=CC=C1)NC2=CC=C(S(NC3=CC=CC=C3Cl)(=O)=O)C(Cl)=C2. InChi Code: InChI=1S/C18H13Cl2N3O3S/c19-13-5-1-2-6-15(13)23-27(25,26)17-9-8-12(11-14(17)20)22-18(24)16-7-3-4-10-21-16/h1-11,23H,(H,22,24). InChi Key: IXHCGJXBIHHIEF-UHFFFAOYSA-N.