Vofopitant dihydrochloride
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Vofopitant dihydrochloride (GR 205171A) is an orally available, selective tachykinin... more
Product information "Vofopitant dihydrochloride"
Description: Vofopitant dihydrochloride (GR 205171A) is an orally available, selective tachykinin NK1 receptor antagonist that inhibits [3H]SP binding to NK1 with pKi values of 9.5 and 10.6, respectively. It is a potential compound for the treatment of pathological vomiting. Target: Neurokinin receptor. Smiles: Cl.Cl.COc1ccc(cc1CN[C@H]1CCCN[C@H]1c1ccccc1)-n1nnnc1C(F)(F)F. References: Gardner CJ, et al. GR205171: a novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity. Regul Pept. 1996 Aug 27,65(1):45-53.
| Keywords: | Vofopitant 2HCl, GR 205171A |
| Supplier: | TargetMol |
| Supplier-Nr: | T13329L |
Properties
| Application: | Targets tachykinin receptor 1 (TACR1) |
| MW: | 505.36 D |
| Formula: | C21H25Cl2F3N6O |
Database Information
| CAS : | 168266-51-1| Matching products |
| KEGG ID : | K04222 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H318, H372, H412 |
| P Phrases: | P260, P264, P270, P273, P280, P310, P314, P305+P351+P338, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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