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Vitamin D3 is a biologically inactive precursor to calcitriol (Cay-71820) that is converted to... more
Product information "Vitamin D3"
Vitamin D3 is a biologically inactive precursor to calcitriol (Cay-71820) that is converted to active metabolites in vivo. Vitamin D3 is obtained from dietary sources, including fish, or formed in the epidermis via photolytic conversion of 7-dehydro cholesterol (Cay-14612) to previtamin D3 by UVB radiation, followed by isomerization to vitamin D3. Vitamin D3 can then be converted to 25-hydroxy vitamin D3 (Cay-9000683) in the liver by the cytochrome P450 (CYP) isoform CYP2R1 before being converted to calcitriol by CYP27B1 in the kidney. Formulations containing vitamin D3 have been used in the treatment of osteoporosis.Formal Name: 3Z-[2E-[(1R,3aS,7aR)-1S-[1R,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexanol. CAS Number: 67-97-0. Synonyms: Cholecalciferol, NSC 375571. Molecular Formula: C27H44O. Formula Weight: 384.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 2 mg/ml, Ethanol: 30 mg/ml. lambdamax: 213, 265 nm. SMILES: C=C1CC[C@H](O)C/C1=C/C=C2[C@@](CC[C@@]3([C@H](C)CCCC(C)C)[H])([H])[C@]3(C)CCC/2. InChi Code: InChI=1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1. InChi Key: QYSXJUFSXHHAJI-YRZJJWOYSA-N. Origin: Animal/Lanolin.
Keywords: | Cholecalciferol, NSC 375571, 3Z-[2E-[(1R,3aS,7aR)-1S-[1R,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexanol |
Supplier: | Cayman Chemical |
Supplier-Nr: | 11792 |
Properties
Application: | Metabolic studies |
MW: | 384.6 D |
Formula: | C27H44O |
Purity: | >98% |
Format: | Crystalline Solid |
Database Information
CAS : | 67-97-0| Matching products |
KEGG ID : | K08539 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
|
H Phrases: | H301, H311, H330, H372 |
P Phrases: | P260, P264, P270, P271, P280, P284, P301+310, P302+352, P304+340, P310, P312, P314, P320, P321, P330, P361+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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