Virginiamycin S1

Description: Virginiamycin S1, a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis by interfering with aminoacyl-tRNA binding and peptide bond formation. Target: Others. Smiles: [H][C@@]12CCCN1C(=O)[C@H](CC)NC(=O)[C@@H](NC(=O)c1ncccc1O)[C@H](C)OC(=O)[C@@]([H])(NC(=O)[C@]1([H])CC(=O)CCN1C(=O)[C@H](Cc1ccccc1)N(C)C2=O)c1ccccc1. References: Ningsih F, et al. VisG is essential for biosynthesis of virginiamycin S, a streptogramin type B antibiotic, as a provider of the nonproteinogenic amino acid phenylglycine. Microbiology. 2011 Nov,157(Pt 11):3213-20.