VH-298

Item number	Size	Delivery time	Price
TGM-TQ0121-2mg	2 mg	7 - 10 business days*	40.00€
TGM-TQ0121-5mg	5 mg	7 - 10 business days*	72.00€
TGM-TQ0121-1mL	1 ml	7 - 10 business days*	83.00€
TGM-TQ0121-10mg	10 mg	7 - 10 business days*	120.00€
TGM-TQ0121-25mg	25 mg	7 - 10 business days*	228.00€
TGM-TQ0121-50mg	50 mg	7 - 10 business days*	371.00€
TGM-TQ0121-100mg	100 mg	7 - 10 business days*	621.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Description: VH-298 is a potent inhibitor of VHL that stabilizes HIF-alpha and elicits a hypoxic... more

Close menu

Product information "VH-298"

Description: VH-298 is a potent inhibitor of VHL that stabilizes HIF-alpha and elicits a hypoxic response via a different mechanism, that is the blockade of the VHL:HIF-alpha protein-protein interaction downstream of HIF-alpha hydroxylation by PHD enzymes. Target: HIF, Ligand for E3 Ligase, Others. Smiles: Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(CC2)C#N)C(C)(C)C)cc1. References: Frost J, et al. Potent and selective chemical probe of hypoxic signalling downstream of HIF-alpha hydroxylation via VHL inhibition. Nat Commun. 2016 Nov 4,7:13312.

Supplier:	TargetMol
Supplier-Nr:	TQ0121

Properties

Application:	Protac(R) reagent
MW:	523.65 D
Formula:	C27H33N5O4S

Database Information

CAS :	2097381-85-4\| Matching products
KEGG ID :	K03871 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

Information about the product reference will follow. more

Close menu

You will get a certificate here

Go back

Read, write and discuss reviews... more

Close menu

Customer review for "VH-298"

Write a review