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![Verapamil (hydrochloride)](https://www.biomol.com/media/image/4b/80/9b/Cay14288-1_600x600.png)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay14288-1 | 1 g | - |
6 - 10 business days* |
39.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Verapamil is the prototypical blocker of L-type calcium channels that produces... more
Product information "Verapamil (hydrochloride)"
Verapamil is the prototypical blocker of L-type calcium channels that produces excitation-contraction uncoupling in cardiac muscle by preventing the slow-inward current of calcium ions. Verapamil can also block calcium fluxes in vascular smooth muscle. It has both peripheral and coronary vasodilator effects (IC50 = 0.38 µM in guinea pig aortic strip) and has been used to control hypertension, angina, cardiac arrhythmia, and vascular headaches. Verapamil has also been used in cell biology as an inhibitor of drug efflux pump proteins such as P-glycoprotein, which are often over-expressed in certain tumor cell lines.Formal Name: alpha-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-alpha-(1-methylethyl)-benzeneacetonitrile, monohydrochloride. CAS Number: 152-11-4. Synonyms: NSC 272366, NSC 657799, (±)-Verapamil. Molecular Formula: C27H38N2O4 . HCl. Formula Weight: 491.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 16.7 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 0.25 mg/ml. lambdamax: 205, 231, 280 nm. SMILES: COC1=CC=C(C(C(C)C)(C#N)CCCN(C)CCC2=CC=C(OC)C(OC)=C2)C=C1OC.Cl. InChi Code: InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6,/h9-12,17-18,20H,8,13-16H2,1-7H3,1H. InChi Key: DOQPXTMNIUCOSY-UHFFFAOYSA-N.
Keywords: | NSC 272366, NSC 657799, alpha-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-alpha-(1-methylethyl)-benzeneacetonitrile, monohydrochloride |
Supplier: | Cayman Chemical |
Supplier-Nr: | 14288 |
Properties
Application: | L-type Calcium channel blocker |
MW: | 491.1 D |
Formula: | C27H38N2O4 . HCl |
Purity: | >98% |
Format: | Crystalline Solid |
Database Information
CAS : | 152-11-4| Matching products |
KEGG ID : | K04850 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
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H Phrases: | H300, H311, H330 |
P Phrases: | P260, P264, P270, P271, P280, P284, P301+310, P302+352, P304+340, P310, P312, P320, P321, P330, P361+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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