Vandetanib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits... more
Product information "Vandetanib"
Description: Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR. Target: Apoptosis, Autophagy, EGFR, VEGFR. Smiles: COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1. References: Wedge SR, et al. ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration. Cancer Res. 2002 Aug 15,62(16):4645-55.
| Keywords: | ZD6474 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1656 |
Properties
| Application: | Targets epidermal growth factor receptor [EC:2.7.10.1] (EGFR, ERBB1) |
| MW: | 475.35 D |
| Formula: | C22H24BrFN4O2 |
Database Information
| CAS : | 443913-73-3| Matching products |
| KEGG ID : | K04361 | Matching products |
| Protein Atlas Nr. : | Tyrosine Phosphorylation |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H360, H373, H410 |
| P Phrases: | P201, P202, P260, P264, P270, P273, P280, P314, P330, P391, P301+P310, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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