Valrubicin
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s:... more
Product information "Valrubicin"
Description: Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 µM) and has antitumor and anti-inflammatory activity. Target: Antibiotic, PKC. Smiles: CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1. References: Chuang LF, et al. Activation of human leukemia protein kinase C by tumor promoters and its inhibition by N-trifluoroacetyladriamycin-14-valerate (AD 32). Biochem Pharmacol. 1992 Feb 18,43(4):865-72.
| Keywords: | AD-32, Valstar |
| Supplier: | TargetMol |
| Supplier-Nr: | T7604 |
Properties
| Application: | Targets DNA topoisomerase II [EC:5.6.2.2] (TOP2) |
| MW: | 723.64 D |
| Formula: | C34H36F3NO13 |
Database Information
| CAS : | 56124-62-0| Matching products |
| KEGG ID : | K03164 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H312, H332, H340, H351, H360 |
| P Phrases: | P201, P202, P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P308+P313, P361+P364, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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