Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
![Valrubicin](https://www.biomol.com/media/image/fd/bf/44/Cay22964-1_600x600.png)
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Valrubicin is a semisynthetic anthracycline antitumor antibiotic and derivative of doxorubicin... more
Product information "Valrubicin"
Valrubicin is a semisynthetic anthracycline antitumor antibiotic and derivative of doxorubicin (Cay-15007). It inhibits the growth of human bladder tumor cell lines with LD50 values ranging from 0.05 to 11.2 µM. Valrubicin is more active against cells in the plateau growth phase than in the log growth phase (LD70s = 2.5 and 12.1 µM, respectively for CUB-2 cells). Valrubicin (40 mg/kg) increases survival in mice with murine P388 and L1210 leukemias. Topical administration of valrubicin (0.01 g/ml) reduces epidermal thickness and normalizes epidermal morphology in a mouse psoriasis xenograft transplantation model. Formulations containing valrubicin have been used in the treatment of bladder cancer.Formal Name: pentanoic acid, 2-[(2S,4S)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-[[2,3,6-trideoxy-3-[(2,2,2-trifluoroacetyl)amino]-alpha-L-lyxo-hexopyranosyl]oxy]-2-naphthacenyl]-2-oxoethyl ester. CAS Number: 56124-62-0. Synonyms: NSC 246131, N-Trifluoroacetyladriamycin-14-valerate. Molecular Formula: C34H36F3NO13. Formula Weight: 723.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: :, DMF: 5 mg/ml, DMSO: 5 mg/ml, Ethanol: 5 mg/ml. lambdamax: 201, 235, 252, 496 nm. SMILES: OC1=C(C[C@](C(COC(CCCC)=O)=O)(O)C[C@@H]2O[C@@](O[C@@H](C)[C@H]3O)([H])C[C@@H]3NC(C(F)(F)F)=O)C2=C(O)C(C4=O)=C1C(C5=CC=CC(OC)=C45)=O. InChi Code: InChI=1S/C34H36F3NO13/c1-4-5-9-21(40)49-13-20(39)33(47)11-16-24(19(12-33)51-22-10-17(27(41)14(2)50-22)38-32(46)34(35,36)37)31(45)26-25(29(16)43)28(42)15-7-6-8-18(48-3)23(15)30(26)44/h6-8,14,17,19,22,27,41,43,45,47H,4-5,9-13H2,1-3H3,(H,38,46)/t14-,17-,19-,22-,27+,33-/m0/s1. InChi Key: ZOCKGBMQLCSHFP-KQRAQHLDSA-N.
Keywords: | NSC 246131, N-Trifluoroacetyladriamycin-14-valerate, pentanoic acid, 2-[(2S,4S)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-[[2,3,6-trideoxy-3-[(2,2,2-trifluoroacetyl)amino]-alpha-L-lyxo-hexopyranosyl]oxy]-2-naphthacenyl]-2-oxoethyl es |
Supplier: | Cayman Chemical |
Supplier-Nr: | 22964 |
Properties
Application: | Antitumor antibiotic, Anthracycline antineoplastic |
MW: | 723.6 D |
Formula: | C34H36F3NO13 |
Purity: | >98% |
Format: | Crystalline Solid |
Database Information
CAS : | 56124-62-0| Matching products |
KEGG ID : | K03164 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
![]() ![]() |
H Phrases: | H301, H312, H332, H340, H351, H360 |
P Phrases: | P201, P202, P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P308+313, P312, P321, P330, P361+364, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed