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Description: USP8-IN-3 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with IC50 of 4.0 µM against USP8D. USP8-IN-3 inhibited the proliferation of GH3 and H1957 cells with GI50 values of 37.03 µM and 6.01 µM, respectively. USP8-IN-3 is a potential compound for the treatment of cancer and viral infections. Target: DUB. Smiles: C(F)(F)(F)C1=NC(=CC=C1)N2CCC(NC(NC3=CC=C(N(=O)=O)C=C3)=S)CC2. References: Li zhiyun, et al. Preparing method and application of USP8 inhibitor: China, CN111138358 A. 2020-05-12
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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