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Description: URAT1 inhibitor 7 is a novel and potent inhibitor of the human uric acid transporter protein URAT1 (IC50:12 nM).URAT1 inhibitor 7 inhibits CYP2C9 with an IC50 of 4.2 µM.URAT1 inhibitor 7 can be used to study hyperuricemia and gout. Target: OAT. Smiles: N#CC1=CC=C(OC2=CC=C(C=C2C#N)S(=O)(=O)NC3=NC=C(F)C=C3)C=C1Cl. References: Storer R I, et al. The discovery and evaluation of diaryl ether heterocyclic sulfonamides as URAT1 inhibitors for the treatment of gout. MedChemComm, 2016:10.1039.C6MD00190D.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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