Umibecestat

Item number	Size	Delivery time	Price
TGM-T13253-1mg	1 mg	7 - 10 business days*	175.00€
TGM-T13253-5mg	5 mg	7 - 10 business days*	371.00€
TGM-T13253-1mL	1 ml	7 - 10 business days*	453.00€
TGM-T13253-10mg	10 mg	7 - 10 business days*	538.00€
TGM-T13253-25mg	25 mg	7 - 10 business days*	897.00€
TGM-T13253-50mg	50 mg	7 - 10 business days*	1,220.00€
TGM-T13253-100mg	100 mg	7 - 10 business days*	1,650.00€

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Description: Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1... more

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Product information "Umibecestat"

Description: Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of alzheimer's disease. Target: BACE. Smiles: C[C@]1(CO[C@](C)(C(N)=N1)C(F)(F)F)c1nc(NC(=O)c2ncc(cc2Cl)C(F)(F)F)ccc1F. References: Neumann U, et al. The BACE-1 inhibitor CNP520 for prevention trials in Alzheimer's disease. EMBO Mol Med. 2018 Nov,10(11). pii: e9316.

Keywords:	CNP520
Supplier:	TargetMol
Supplier-Nr:	T13253

Properties

Application:	Targets beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:3.4.23.46] (BACE1)
MW:	513.8 D
Formula:	C19H15ClF7N5O2

Database Information

CAS :	1387560-01-1\| Matching products
KEGG ID :	K04521 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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