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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
CDX-U0027-M050 | 50 mg | - | - |
3 - 9 business days* |
191.00€
|
||
CDX-U0027-M100 | 100 mg | - | - |
3 - 9 business days* |
321.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
White to light yellow crystalline powder. Soluble in DMSO (30mg/ml), ethanol (30mg/ml) or DMF... more
Product information "Ulipristal acetate"
White to light yellow crystalline powder. Soluble in DMSO (30mg/ml), ethanol (30mg/ml) or DMF (30mg/ml). Chemical. CAS: 126784-99-4. Formula: C30H37NO4. MW: 475.62. Synthetic. Ulipristal acetate is a selective progesterone receptor modulator (SPRM) that binds to the human progesterone receptors PR-A and PR-B (EC50s=8.5 and 7.7nM, respectively), rabbit uterine PR (EC50=13.6nM), and rabbit thymic glucocorticoid receptor (GR, EC50=15.4nM). It is selective for human progesterone receptors over the human estrogen receptor (ER, EC50>10,000nM). It inhibits growth of IGROV-1 and SKOV3 human ovarian cancer cells (IC50s=15.5 and 31.5µM, respectively) even after resistance to combined cisplatin and paclitaxel treatment has developed. Ulipristal acetate reverses the proliferative effect of progesterone on patient-derived germline mutant BRCA1 breast tissue xenografts in ovariectomized athymic mice. Formulations containing ulipristal acetate have been used as emergency contraceptives and to treat uterine fibroids.
Keywords: | (11beta)-17-(Acetyloxy)-11-[4-(dimethylamino)phenyl]-19-norpregna-4,9-diene-3,20-dione, CDB-2914, HRP 2000, RU 44675 |
Supplier: | Chemodex |
Supplier-Nr: | U0027 |
Properties
Host: | Synthetic |
MW: | 475,62 D |
Formula: | C30H37NO4 |
Purity: | >98% (HPLC) |
Format: | Solid |
Database Information
CAS : | 126784-99-4| Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Signal Word: | Warning |
GHS Hazard Pictograms: |
|
H Phrases: | H361fd |
P Phrases: | P280 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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