UK-5099
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: UK-5099 (PF-1005023) is a specific and potent inhibitor of MPC carrier activity,... more
Product information "UK-5099"
Description: UK-5099 (PF-1005023) is a specific and potent inhibitor of MPC carrier activity, effectively inhibiting pyruvate-dependent oxygen consumption in rat heart mitochondria with an IC50 of 50 nM [1]. Target: Others, Mitochondrial Metabolism. Smiles: OC(=O)C(=Cc1cn(-c2ccccc2)c2ccccc12)C#N. References: Patterson JN, et al. Mitochondrial metabolism of pyruvate is essential for regulating glucose-stimulated insulin secretion. J Biol Chem. 2014 May 9,289(19):13335-46.
| Keywords: | UK5099, UK 5099, PF-1005023 |
| Supplier: | TargetMol |
| Supplier-Nr: | T4441 |
Properties
| Application: | Potent, specific mitochondrial pyruvate carrier inhibitor |
| MW: | 288.3 D |
| Formula: | C18H12N2O2 |
Database Information
| CAS : | 56396-35-1| Matching products |
| KEGG ID : | K22138 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H410 |
| P Phrases: | P264, P270, P273, P301+310, P330, P391, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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