UK 5099
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Potent and specific inhibitor of the mitochondrial pyruvate carrier (MPC), blocking pyruvate from... more
Product information "UK 5099"
Potent and specific inhibitor of the mitochondrial pyruvate carrier (MPC), blocking pyruvate from entering the mitochondria, consequently promoting lactate production. Inhibitor of tricarboxylic acid (TCA) cycle. Plasma membrane monocarboxylate transporters (MCTs) inhibitor, but with Ki values some two or three orders of magnitude higher than those for the inhibition of the MPC. Inhibits mitochondrial lactate and pyruvate transport. Decreases glycolysis. Useful agent for immunometabolism research.
| Keywords: | PF-1005023, 2-Cyano-3-(1-phenyl-1H-indol-3-yl)-2-propenoic acid |
| Supplier: | AdipoGen Life Sciences |
| Supplier-Nr: | AG-CR1-3691 |
Properties
| Application: | Potent, specific mitochondrial pyruvate carrier inhibitor |
| MW: | 288.3 D |
| Formula: | C18H12N2O2 |
| Purity: | >95% |
| Format: | Solid |
Database Information
| CAS : | 56396-35-1| Matching products |
| KEGG ID : | K22138 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H312, H317, H319, H335 |
| P Phrases: | P261, P264, P271, P272, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P333+P313, P337+P313, P361+P364, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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