UDP-alpha-D-Galactose (sodium salt)

UDP-alpha-D-galactose is an endogenous nucleotide sugar that is used by glycosyltransferases to transfer alpha-D-galactose residues to substrates. It is an agonist of the purinergic P2Y14 receptor (EC50 = 0.67 µM), an atypical P2Y receptor involved in the activation of dendritic and glial cells. Levels of UDP-alpha-D-galactose in red blood cells are decreased in patients with phenylketonuria (PKU) and maple syrup urine disease, inborn errors of amino acid metabolism characterized by mutations in the gene encoding phenylalanine hydroxylase (PAH) and a deficiency in the branched-chain alpha-keto acid dehydrogenase enzyme complex, respectively.Formal Name: uridine 5'-(trihydrogen diphosphate), sodium salt, P'-alpha-D-galactopyranosyl ester. CAS Number: 137868-52-1. Synonyms: UDP-Gal, Uridine-5'-diphosphate-alpha-D-Galactose. Molecular Formula: C15H22N2O17P2 . 2Na. Formula Weight: 610.3. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 263 nm. SMILES: O[C@H]1[C@@](N2C(NC(C=C2)=O)=O)([H])O[C@@H]([C@H]1O)COP(OP(O[C@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO)([O-])=O)([O-])=O.[Na+].[Na+]. InChi Code: InChI=1S/C15H24N2O17P2.2Na/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25,,/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25),,/q,2*+1/p-2/t5-,6-,8+,9-,10+,11-,12-,13-,14-,,/m1../s1. InChi Key: PKJQEQVCYGYYMM-QKYKBPIOSA-L.