Tyrosol

Tyrosol is a phenol that has been found in olives and olive oil and has diverse biological activities. It is fungicidal against H. capsulatum and C. posadasii with minimum fungicidal concentration (MFC) values of 170-710 and 1,420 µg/ml, respectively. Tyrosol (70-280 mg/kg) increases survival and pulmonary superoxide dismutase (SOD) activity and decreases pulmonary macrophage and neutrophil infiltration, edema, inflammation, and myeloperoxidase (MPO) activity in a mouse model of LPS-induced acute lung injury. It reduces aqueous humor TNF-alpha, nitric oxide (NO), and prostaglandin E2 (PGE2, Cay-14010) levels and cellular infiltration in a rat model of ocular endotoxin-induced uveitis (EIU). Tyrosol also decreases erythrocyte aggregation, increases the oxygen transport capacity index (OTCI), and abolishes cortical microvascular rarefaction in spontaneously hypertensive rats.Formal Name: 4-hydroxy-benzeneethanol. CAS Number: 501-94-0. Synonyms: NSC 59876, p-HPEA. Molecular Formula: C8H10O2. Formula Weight: 138.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 5 mg/ml, PBS (pH 7.2): 3 mg/ml. lambdamax: 225, 279 nm. SMILES: OC1=CC=C(CCO)C=C1. InChi Code: InChI=1S/C8H10O2/c9-6-5-7-1-3-8(10)4-2-7/h1-4,9-10H,5-6H2. InChi Key: YCCILVSKPBXVIP-UHFFFAOYSA-N. Origin: Synthetic.