TTP 22

TTP 22 is a thienopyrimidine compound that inhibits casein kinase 2 (CK2) with an IC50 value of 100 nM (Ki = 40 nM). It displays selectivity for CK2 over JNK3, ROCK1, and MET with no inhibitory effects towards these kinases at 10 µM.Formal Name: 3-[[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio]-propanoic acid. CAS Number: 329907-28-0. Molecular Formula: C16H14N2O2S2. Formula Weight: 330.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml, Ethanol: 2 mg/ml. lambdamax: 232, 300 nm. SMILES: CC(C=C1)=CC=C1C2=CSC3=NC=NC(SCCC(O)=O)=C32. InChi Code: InChI=1S/C16H14N2O2S2/c1-10-2-4-11(5-3-10)12-8-22-16-14(12)15(17-9-18-16)21-7-6-13(19)20/h2-5,8-9H,6-7H2,1H3,(H,19,20). InChi Key: RAOULLCLLOGTDA-UHFFFAOYSA-N.