Trospium (chloride)

Trospium is an antagonist of muscarinic (M) receptors (Kis = 0.50-2.3 nM for human M1-5 recombinant receptors, respectively). Formulations containing antimuscarinics, including trospium, are used to manage overactive bladder by relieving urgency, frequency, and incontinence.Formal Name: (1alpha,3beta,5alpha)-3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium], monochloride. CAS Number: 10405-02-4. Synonyms: Relaspium. Molecular Formula: C25H30NO3 . Cl. Formula Weight: 428.0. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 0.16 mg/ml, Ethanol: 0.2 mg/ml, PBS (pH 7.2): 1 mg/ml. SMILES: O=C(C(C1=CC=CC=C1)(O)C2=CC=CC=C2)OC3C[C@]([N+]45CCCC4)([H])CC[C@@]5([H])C3.[Cl-]. InChi Code: InChI=1S/C25H30NO3.ClH/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26,/h1-6,9-12,21-23,28H,7-8,13-18H2,1H/q+1,/p-1/t21-,22-,/m0./s1. InChi Key: RVCSYOQWLPPAOA-VROPFNGYSA-M.