Tropifexor

Item number	Size	Manual	Delivery time	Price
TGM-T4379-1mg	1 mg	-	7 - 10 business days*	87.00€
TGM-T4379-5mg	5 mg	-	7 - 10 business days*	165.00€
TGM-T4379-1mL	1 ml	-	7 - 10 business days*	220.00€
TGM-T4379-10mg	10 mg	-	7 - 10 business days*	255.00€
TGM-T4379-25mg	25 mg	-	7 - 10 business days*	450.00€
TGM-T4379-50mg	50 mg	-	7 - 10 business days*	686.00€
TGM-T4379-100mg	100 mg	-	7 - 10 business days*	1,039.00€
TGM-T4379-200mg	200 mg	-	7 - 10 business days*	1,569.00€
TGM-T4379-500mg	500 mg	-	7 - 10 business days*	2,326.00€

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Description: Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2... more

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Product information "Tropifexor"

Description: Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM. Target: Autophagy, FXR. Smiles: OC(=O)c1cc(F)c2nc(sc2c1)N1[C@H]2CC[C@@H]1C[C@@H](C2)OCc1c(onc1-c1ccccc1OC(F)(F)F)C1CC1. References: Tully DC,etal.Discovery of Tropifexor (LJN452), a Highly Potent Non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH).J Med Chem. 2017 Dec 28,60(24):9960-9973.

Keywords:	LJN452
Supplier:	TargetMol
Supplier-Nr:	T4379

Properties

Application:	Targets farnesoid X receptor (NR1H4, FXR)
MW:	603.58 D
Formula:	C29H25F4N3O5S

Database Information

CAS :	1383816-29-2\| Matching products
KEGG ID :	K08537 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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