Trifluorothymidine

Trifluorothymidine is a derivative of thymidine that exhibits antiviral and anticancer activity by inhibiting thymidylate synthase, thereby blocking nucleic acid synthesis, and by incorporating into DNA, which leads to DNA damage and apoptosis.Formal Name: alpha,alpha,alpha-trifluoro-thymidine. CAS Number: 70-00-8. Synonyms: NSC 75520, NSC 529182, TFT, Trifluridine. Molecular Formula: C10H11F3N2O5. Formula Weight: 296.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 16 mg/ml, DMSO: 10 mg/ml, PBS (pH 7.2): 5 mg/ml. lambdamax: 262 nm. SMILES: O=C(C(C(F)(F)F)=CN1[C@@H]2O[C@H](CO)[C@@H](O)C2)NC1=O. InChi Code: InChI=1S/C10H11F3N2O5/c11-10(12,13)4-2-15(9(19)14-8(4)18)7-1-5(17)6(3-16)20-7/h2,5-7,16-17H,1,3H2,(H,14,18,19)/t5-,6+,7+/m0/s1. InChi Key: VSQQQLOSPVPRAZ-RRKCRQDMSA-N.