Tofacitinib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Tofacitinib (Tasocitinib) is a Janus kinase inhibitor that inhibits JAK3/2/1... more
Product information "Tofacitinib"
Description: Tofacitinib (Tasocitinib) is a Janus kinase inhibitor that inhibits JAK3/2/1 (IC50=1/20/112 nM) and is orally active. Tofacitinib is used for the treatment of moderate to severe rheumatoid arthritis. Target: JAK, Apoptosis, ROCK, Src. Smiles: C[C@@H]1CCN(C[C@@H]1N(C)C1=C2C=CNC2=NC=N1)C(=O)CC#N. References: Changelian PS, et al, Science, 2003, 302(5646), 875-878.
| Keywords: | CP-690550, Tasocitinib |
| Supplier: | TargetMol |
| Supplier-Nr: | T6321 |
Properties
| Application: | Targets Janus kinase 1 [EC:2.7.10.2] (JAK1) |
| MW: | 312.37 D |
| Formula: | C16H20N6O |
Database Information
| CAS : | 477600-75-2| Matching products |
| KEGG ID : | K04447 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H311, H315, H319, H331, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P311, P312, P321, P330, P301+P310, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P361+P364, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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