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Description: TK05 is a potent and selective leukotriene C4 synthase (LTC4S) inhibitor with an IC50 of 95 nM. Target: Others. Smiles: COc1ccc(cc1)C(=O)c1ccc(cc1C(O)=O)C(=O)c1ccc(cn1)N(CC1CC1)c1ccc(Cl)cc1. References: Kleinschmidt TK, et al. Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human Leukotriene C4 Synthase. J Pharmacol Exp Ther. 2015 Oct,355(1):108-16.
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