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Tirabrutinib

TargetMol
Tirabrutinib
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-TQ0236-5mg 5 mg -

7 - 10 business days*

41.00€
TGM-TQ0236-1mL 1 ml

7 - 10 business days*

45.00€
TGM-TQ0236-10mg 10 mg

7 - 10 business days*

72.00€
TGM-TQ0236-25mg 25 mg

7 - 10 business days*

123.00€
TGM-TQ0236-50mg 50 mg

7 - 10 business days*

201.00€
TGM-TQ0236-100mg 100 mg

7 - 10 business days*

371.00€
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
 
Description Product Citations Certificate of Analysis Reviews 0
Description
Description: Tirabrutinib (GS-4059) (ONO-4059) is an orally active Bruton's Tyrosine Kinase (Btk)... more
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Product information "Tirabrutinib"
Description: Tirabrutinib (GS-4059) (ONO-4059) is an orally active Bruton's Tyrosine Kinase (Btk) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib irreversibly and covalently binds to Btk and inhibits aberrant B cell receptor signaling. Tirabrutinib can be used in studies of autoimmune diseases and hematological malignancies. Target: BTK. Smiles: CC#CC(=O)N1CC[C@H](C1)n1c2ncnc(N)c2n(-c2ccc(Oc3ccccc3)cc2)c1=O. References: Yu H, et al. Bruton's tyrosine kinase inhibitors in primary central nervous system lymphoma-evaluation of anti-tumor efficacy and brain distribution. Transl Cancer Res. 2021 May,10(5):1975-1983.
Keywords: ONO-4059, Velexbru, GS-4059
Supplier: TargetMol
Supplier-Nr: TQ0236

Properties

Application: Targets Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2] (BTK)
MW: 454.48 D
Formula: C25H22N6O3

Database Information

CAS : 1351636-18-4| Matching products
KEGG ID : K07370 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Product Citations
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