Tipranavir
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1... more
Product information "Tipranavir"
Description: Tipranavir is a protease inhibitor that inhibits HIV-1 resistant to more than 1 protease inhibitor .Tipranavir effectively inhibits HIV-1 protease enzyme activity and dimerisation and has potent activity against multiple protease inhibitor (PI) HIV-1 isolates (IC50 of 66-410 nM). Tipranavir inhibits SARS-CoV-2 3CLpro activity. Target: HIV Protease, SARS-CoV. Smiles: CCC[C@@]1(CCc2ccccc2)CC(O)=C([C@H](CC)c2cccc(NS(=O)(=O)c3ccc(cn3)C(F)(F)F)c2)C(=O)O1. References: Aoki M, et al. Loss of the protease dimerization inhibition activity of tipranavir (TPV) and its association with the acquisition of resistance to TPV by HIV-J Virol. 2012 , 86(24):13384-13396.
| Keywords: | PNU-140690 |
| Supplier: | TargetMol |
| Supplier-Nr: | T4578 |
Properties
| Application: | Targets HIV protease [EC:3.4.23.16 3.4.23.47] (PR) |
| MW: | 602.66 D |
| Formula: | C31H33F3N2O5S |
Database Information
| CAS : | 174484-41-4| Matching products |
| KEGG ID : | K22599 | Matching products |
| Protein Atlas Nr. : | Microbiology |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| GHS Hazard Pictograms: |
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| H Phrases: | H411 |
| P Phrases: | P273, P391, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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