Tipifarnib

Item number	Size	Delivery time	Price
TGM-T6271-1mg	1 mg	7 - 10 business days*	34.00€
TGM-T6271-2mg	2 mg	7 - 10 business days*	48.00€
TGM-T6271-5mg	5 mg	7 - 10 business days*	76.00€
TGM-T6271-1mL	1 ml	7 - 10 business days*	82.00€
TGM-T6271-10mg	10 mg	7 - 10 business days*	130.00€
TGM-T6271-25mg	25 mg	7 - 10 business days*	247.00€
TGM-T6271-50mg	50 mg	7 - 10 business days*	448.00€

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Description: Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential... more

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Product information "Tipifarnib"

Description: Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting the farnesylation of proteins, this agent prevents the activation of Ras oncogenes, inhibits cell growth, induces apoptosis, and inhibits angiogenesis. Target: Transferase. Smiles: Cn1cncc1[C@@](N)(c1ccc(Cl)cc1)c1ccc2n(C)c(=O)cc(-c3cccc(Cl)c3)c2c1. References: Margolin KA, et al. Clin Cancer Res. 2012, 18(4), 1129-1137.

Keywords:	Zarnestra, R115777, IND 58359
Supplier:	TargetMol
Supplier-Nr:	T6271

Properties

Application:	Antineoplastic
MW:	489.4 D
Formula:	C27H22Cl2N4O

Database Information

CAS :

192185-72-1| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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