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Ticlopidine is a thienopyridine P2Y12 receptor antagonist. It inhibits aggregation of human platelets induced by collagen, arachidonic acid (Cay-90010), and ADP (Cay-16778, IC50s = 75, 600, and 1,300 µM, respectively). It also inhibits ADP-induced aggregation of rat platelets and decreases thrombus weight in vivo in a rat model of arterio-venous shunt thrombosis when administered at a dose of 100 mg/kg. Ticlopidine (300 mg/kg) inhibits healing of acetic acid-induced gastric ulcers in rats. Formulations containing ticlopidine have been used in the prevention of thrombotic stroke.Formal Name: 5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine, monohydrochloride. CAS Number: 53885-35-1. Molecular Formula: C14H14ClNS . HCl. Formula Weight: 300.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 0.5 mg/ml, PBS (pH 7.2): 0.1 mg/ml. SMILES: ClC1=C(CN2CCC(SC=C3)=C3C2)C=CC=C1.Cl. InChi Code: InChI=1S/C14H14ClNS.ClH/c15-13-4-2-1-3-11(13)9-16-7-5-14-12(10-16)6-8-17-14,/h1-4,6,8H,5,7,9-10H2,1H. InChi Key: MTKNGOHFNXIVOS-UHFFFAOYSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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