TG6-129

TG6-129
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T28958-1mg 1 mg -

7 - 10 business days*

120.00€
TGM-T28958-5mg 5 mg -

7 - 10 business days*

247.00€
TGM-T28958-1mL 1 ml -

7 - 10 business days*

349.00€
TGM-T28958-10mg 10 mg -

7 - 10 business days*

439.00€
TGM-T28958-25mg 25 mg -

7 - 10 business days*

724.00€
TGM-T28958-50mg 50 mg -

7 - 10 business days*

967.00€
TGM-T28958-100mg 100 mg -

7 - 10 business days*

1,363.00€
TGM-T28958-500mg 500 mg -

7 - 10 business days*

2,768.00€
 
Description: TG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced... more
Product information "TG6-129"
Description: TG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 µM. TG6-129 reduces the expression of COX-2, IL-1beta, IL-6, IL-12, IL-23 and TNF-alpha induced by the EP2-selective agonist butaprost in P388D1 macrophages. Target: Prostaglandin Receptor. Smiles: CCC1=NN=C(NS(=O)(=O)C2=CC=C(NC(=S)NC(=O)\C=C\C3=CC=C(F)C=C3)C=C2)S1. References: Ganesh T, Jiang J, Shashidharamurthy R, Dingledine R. Discovery and characterization of carbamothioylacrylamides as EP(2) selective antagonists. ACS Med Chem Lett. 2013 Jul 11,4(7):616-621. PubMed PMID: 23914286, PubMed Central PMCID: PMC3731160.
Keywords: TG6 129
Supplier: TargetMol
Supplier-Nr: T28958

Properties

Application: EP2 receptor antagonist
MW: 491.58 D
Formula: C20H18FN5O3S3

Database Information

CAS : 1164464-14-5| Matching products
KEGG ID : K04259 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "TG6-129"
Write a review
or to review a product.
Viewed