Terpineol

Terpineol is a monoterpene alcohol that has been found in a variety of plants, including Cannabis, and has diverse biological activities. alpha-Terpineol has antibacterial and antinociceptive properties. It is active against a variety of periodontopathic and cariogenic bacteria, including strains of P. gingivalis, F. nucleatum, and A. actinomycetemcomitans (MICs = 0.1-0.8 mg/ml), however, it is toxic to KB cells when used at a concentration of 0.8 mg/ml. It also reduces mechanical hyperalgesia, as well as spontaneous and palpation-induced nociception, in a mouse model of cancer-induced pain beginning on day 5 when administered at a dose of 50 mg/kg per day. Terpinen-4-ol has anticonvulsant properties, inhibiting pentylenetetrazol-induced seizures in mice when used at doses ranging from 50 to 200 mg/kg. alpha-Terpineol and terpinen-4-ol also have anti-inflammatory properties, reducing LPS-induced production of IL-1beta, IL-6, and IL-10, but not TNF-alpha, in U937 cells. This product is a mixture of alpha-, beta-, and gamma-terpineol.Formal Name: alpha,alpha,4-trimethyl-3-cyclohexene-1-methanol, 1-methyl-4-(1-methylethenyl)-cyclohexanol, 1-methyl-4-(1-methylethylidene)-cyclohexanol. CAS Number: 8000-41-7. Molecular Formula: C10H18O. Formula Weight: 154.3. Purity: >90% (mixture of isomers). Formulation: (Request formulation change), An oil. Solubility: Chloroform: Slightly soluble, Ethanol: Slightly soluble, Methanol: Slightly soluble. SMILES: CC(O)(C)C1CCC(C)=CC1.C=C(C)C2CCC(C)(O)CC2.C/C(C)=C3CCC(C)(O)CC/3. InChi Code: InChI=1S/3C10H18O/c1-8-4-6-9(7-5-8)10(2,3)11,2*1-8(2)9-4-6-10(3,11)7-5-9/h4,9,11H,5-7H2,1-3H3,11H,4-7H2,1-3H3,9,11H,1,4-7H2,2-3H3. InChi Key: NGVQETRGDCKEAH-UHFFFAOYSA-N.