Talniflumate
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3)... more
Product information "Talniflumate"
Description: Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome. Target: Chloride channel, COX, N-Acetylglucosaminyltransferase, Anion Exchanger. Smiles: O(C(=O)C1=C(NC2=CC(C(F)(F)F)=CC=C2)N=CC=C1)C3C=4C(C(=O)O3)=CC=CC4. References: Knight D. Talniflumate (Genaera)[J]. Current Opinion in Investigational Drugs, 2004, 5(5):557-62.
| Keywords: | Somalgen |
| Supplier: | TargetMol |
| Supplier-Nr: | T4503 |
Properties
| Application: | Analgesic, Antiinflammatory |
| MW: | 414.33 D |
| Formula: | C21H13F3N2O4 |
Database Information
| CAS : | 66898-62-2| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319 |
| P Phrases: | P264, P270, P280, P321, P330, P301+P310, P302+P352, P305+P351+P338, P332+P313, P337+P313, P362+P364, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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