Tadalafil
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Larger quantity required? Request bulk
Description: Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity that... more
Product information "Tadalafil"
Description: Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity that selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase (PDE-5), preventing cGMP degradation in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis, thereby causing prolonged muscle relaxation, vasodilation, and enhanced penile erection. Target: PDE, Apoptosis. Smiles: O=C1N2[C@@H](C3=C(C=4C(N3)=CC=CC4)C[C@@]2(C(=O)N(C)C1)[H])C=5C=C6C(=CC5)OCO6. References: Blount MA, et al. Mol Pharmacol, 2004, 66(1), 144-152.
| Keywords: | Cialis, IC-351 |
| Supplier: | TargetMol |
| Supplier-Nr: | T1398 |
Properties
| Application: | Targets cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35] (PDE5) |
| MW: | 389.4 D |
| Formula: | C22H19N3O4 |
Database Information
| CAS : | 171596-29-5| Matching products |
| KEGG ID : | K13762 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H410 |
| P Phrases: | P264, P270, P273, P330, P391, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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