Tacrolimus
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM)... more
Product information "Tacrolimus"
Description: Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein phosphatase. Target: mTOR, Autophagy, Phosphatase, Antibiotic, Antibacterial, Others. Smiles: CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC. References: Zhu H, et al. Tacrolimus promotes hepatocellular carcinoma and enhances CXCR4/SDF-1alpha expression in vivo. Mol Med Rep. 2014 Aug,10(2):585-92.
| Keywords: | Fujimycin, FK506, FR900506 |
| Supplier: | TargetMol |
| Supplier-Nr: | T2144 |
Properties
| MW: | 804.02 D |
| Formula: | C44H69NO12 |
Database Information
| CAS : | 104987-11-3| Matching products |
| Protein Atlas Nr. : | Adhesion & Structure |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H361, H372 |
| P Phrases: | P201, P202, P260, P264, P270, P280, P314, P321, P330, P301+P310, P308+P313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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