SW155246
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1, IC50... more
Product information "SW155246"
Description: SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1, IC50 of 1.2 µM). SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells. Target: DNA Methyltransferase. Smiles: Oc1ccc(NS(=O)(=O)c2ccc(Cl)c(c2)[N+]([O-])=O)c2ccccc12. References: Medina-Franco J , O Méndez-Lucio, Yoo J . Rationalization of Activity Cliffs of a Sulfonamide Inhibitor of DNA Methyltransferases with Induced-Fit Docking[J]. International Journal of Molecular Sciences, 2014, 15(2).
| Supplier: | TargetMol |
| Supplier-Nr: | T8967 |
Properties
| Application: | DNMT1 antagonist |
| MW: | 378.79 D |
| Formula: | C16H11ClN2O5S |
Database Information
| CAS : | 420092-79-1| Matching products |
| KEGG ID : | K00558 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H319 |
| P Phrases: | P264, P280, P305+351+338, P337+313 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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