Sulfosuccinimidyl Oleate (sodium salt)

Sulfosuccinimidyl oleate (SSO) is an irreversible inhibitor of the fatty acid translocase CD36, blocking uptake of oleate, linoleate, or stearate by about 65% when added at 200 µM to adipocytes. It reduces the uptake of palmitate by mouse insulinoma MIN6 cells, preventing palmitate-induced changes in insulin secretion. SSO impairs saturated fatty acid-induced lipid accumulation and inflammation in RAW 264.7 macrophages.Formal Name: 9-octadecenoic acid, 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester, monosodium salt. CAS Number: 1212012-37-7. Synonyms: SSO. Molecular Formula: C22H36NO7S . Na. Formula Weight: 482.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml. SMILES: CCCCCCCC/C=C\CCCCCCCC(ON1C(C(S(O)(=O)=O)CC1=O)=O)=O.[Na+]. InChi Code: InChI=1S/C22H37NO7S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(25)30-23-20(24)18-19(22(23)26)31(27,28)29,/h9-10,19H,2-8,11-18H2,1H3,(H,27,28,29),/q,+1/b10-9-,. InChi Key: FZVVLJSNKVOPRF-KVVVOXFISA-N.