SU4312
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR... more
Product information "SU4312"
Description: SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 µM respectively). SU4312 (SU 4312) unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS. Target: PDGFR, VEGFR. Smiles: CN(C)c1ccc(\C=C2/C(=O)Nc3ccccc23)cc1. References: Li Y, et al. Vascular Endothelial Growth Factor-A (VEGF-A) Mediates Activin A-Induced Human Trophoblast Endothelial-Like Tube Formation. Endocrinology. 2015 Nov,156(11):4257-68.
| Keywords: | SU 4312, NSC 86429 |
| Supplier: | TargetMol |
| Supplier-Nr: | T3570 |
Properties
| Application: | Selective, cell-permeable VEGFR2 / PDGFR inhibitor |
| MW: | 264.32 D |
| Formula: | C17H16N2O |
Database Information
| CAS : | 5812-07-7| Matching products |
| KEGG ID : | K04363 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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