SU 5205

SU 5205 is an inhibitor of VEGF receptor 2 (VEGFR2/FLK1, IC50 = 9.6 µM). It inhibits human umbilical vein endothelial cell (HUVEC) mitogenesis induced by VEGF or acidic FGF with IC50 values of 0.9 and 0.6 µM, respectively.Formal Name: 3-[(4-fluorophenyl)methylene]-1,3-dihydro-2H-indol-2-one. CAS Number: 3476-86-6. Molecular Formula: C15H10FNO. Formula Weight: 239.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMSO: 50 mg/ml, DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml, Ethanol: 5 mg/ml. SMILES: FC1=CC=C(/C=C2C(NC3=C\2C=CC=C3)=O)C=C1. InChi Code: InChI=1S/C15H10FNO/c16-11-7-5-10(6-8-11)9-13-12-3-1-2-4-14(12)17-15(13)18/h1-9H,(H,17,18)/b13-9-. InChi Key: QIERHADIMMFZNE-LCYFTJDESA-N.