Stachyose (hydrate)

Stachyose is an oligosaccharide and prebiotic. In vivo, stachyose (1 g/kg per day) reduces the number of colonic lesions and serum TNF-alpha, IL-6, IL-10, and IL-17a levels, as well as increases gut levels of Akkermansia and the probiotic Lactobacillus, in a rat model of colitis induced by dextran sulfate (DSS, Cay-23250). It decreases serum LPS, IL-6, and TNF-alpha levels and enriches Phascolarctobacterium, Bilophila, Oscillospira, and Turicibacter in the gut microbiota in a rat model of diabetes induced by high-fat diet and streptozotocin (STZ, Cay-13104). Stachyose also enhances berberine-induced blood glucose control and improvements in insulin resistance, as well as decreases the fecal concentration of short-chain fatty acids, in the KKAgamma mouse model of type 2 diabetes.Formal Name: beta-D-fructofuranosyl O-alpha-D-galactopyranosyl-(1->6)-O-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, hydrate. CAS Number: 54261-98-2. Molecular Formula: C24H42O21 . XH2O. Formula Weight: 666.6. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 1 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: OC[C@]1(O[C@@H]([C@H]([C@@H]1O)O)CO)O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO[C@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO[C@H]4O[C@@H]([C@@H]([C@@H]([C@H]4O)O)O)CO.O. InChi Code: InChI=1S/C24H42O21.H2O/c25-1-6-10(28)14(32)17(35)21(41-6)39-3-8-11(29)15(33)18(36)22(42-8)40-4-9-12(30)16(34)19(37)23(43-9)45-24(5-27)20(38)13(31)7(2-26)44-24,/h6-23,25-38H,1-5H2,1H2/t6-,7-,8-,9-,10+,11+,12-,13-,14+,15+,16+,17-,18-,19-,20+,21+,22+,23-,24+,/m1./s1. InChi Key: YDBMRUQRXAFOAH-KTDNCYJLSA-N.