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Description: SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive properties. SP600125 inhibits autophagy and induces apoptosis. Target: Apoptosis, Aurora Kinase, Autophagy, Ferroptosis, JNK, Trk receptor. Smiles: O=C1C2=C3C(NN=C3C3=C1C=CC=C3)=CC=C2. References: Li CH, et al. Enhancement of radiosensitivity by inhibition of c-Jun N-terminal kinase activity in a Lewis lung carcinoma-bearing subcutaneous tumor mouse model. Oncol Rep. 2016 Dec,36(6):3397-3404.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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