Sotorasib

Item number	Size	Delivery time	Price
TGM-T8684-1mg	1 mg	7 - 10 business days*	31.00€
TGM-T8684-2mg	2 mg	7 - 10 business days*	45.00€
TGM-T8684-5mg	5 mg	7 - 10 business days*	72.00€
TGM-T8684-1mL	1 ml	7 - 10 business days*	88.00€
TGM-T8684-10mg	10 mg	7 - 10 business days*	128.00€
TGM-T8684-25mg	25 mg	7 - 10 business days*	236.00€
TGM-T8684-50mg	50 mg	7 - 10 business days*	392.00€
TGM-T8684-100mg	100 mg	7 - 10 business days*	481.00€
TGM-T8684-500mg	500 mg	7 - 10 business days*	1,080.00€
TGM-T8684-1g	1 g	7 - 10 business days*	1,430.00€

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Description: Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS... more

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Product information "Sotorasib"

Description: Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C. Sotorasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Sotorasib exhibits inhibitory activity against KRAS G12C mutant tumors. Target: Ras. Smiles: CC(C)c1nccc(C)c1-n1c2nc(c(F)cc2c(nc1=O)N1CCN(C[C@@H]1C)C(=O)C=C)-c1c(O)cccc1F. References: Canon J, et al. The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity. Nature. 2019 Nov,575(7781):217-223.

Keywords:	AMG-510
Supplier:	TargetMol
Supplier-Nr:	T8684

Properties

Application:	Targets GTPase KRas (KRAS, KRAS2)
MW:	560.59 D
Formula:	C30H30F2N6O3

Database Information

CAS :	2296729-00-3\| Matching products
KEGG ID :	K07827 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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