SNDX-5613
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: SNDX-5613 is a potent and specific inhibitor of Menin-MLL(Ki of 0.149 nM and a cell... more
Product information "SNDX-5613"
Description: SNDX-5613 is a potent and specific inhibitor of Menin-MLL(Ki of 0.149 nM and a cell based IC50 of 10-20 nM). SNDX-5613 can be used for the research of MLL-rearranged (MLL-r) acute leukemias. Target: Epigenetic Reader Domain, Histone Methyltransferase. Smiles: CCN(C(C)C)C(=O)c1cc(F)ccc1Oc1cncnc1N1CC2(C1)CCN(C[C@H]1CC[C@@H](CC1)NS(=O)(=O)CC)CC2. References: A drug, SNDX-5613, to treat acute leukemia with a KMT2A translocation or an NPM1 mutation that has come back (relapsed) or has not gotten better with treatment (refractory).
| Supplier: | TargetMol |
| Supplier-Nr: | T12943 |
Properties
| Application: | Targets menin (MEN1, MNN1) |
| MW: | 630.82 D |
| Formula: | C32H47FN6O4S |
Database Information
| CAS : | 2169919-21-3| Matching products |
| KEGG ID : | K14970 | Matching products |
| Protein Atlas Nr. : | Gene Regulation |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H410 |
| P Phrases: | P264, P270, P273, P330, P391, P301+P310, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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