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Description: SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 µM/0.22 µM, able to transport through the blood-brain barrier. Target: DNA/RNA Synthesis, MEK. Smiles: NC(Sc1ccc(N)cc1)=C(C#N)c1ccccc1C(F)(F)F. References: Scherle PA, wt al. J Biol Chem. 2000, 275(47), 37086-37092.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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