SKF 83566 (hydrobromide)

SKF 83566 is a dopamine D1 receptor antagonist. In vivo, SKF 83566 (0.005, 0.01, and 0.03 mg/kg) reduces dexbenzetimide- and scopolamine-induced locomotor stereotypy in rats. It decreases ghrelin-induced increases in novel object exploration and food intake in rats when administered at a dose of 100 µg/kg. SKF 83566 also reduces schedule-induced polydipsia in rats.Formal Name: 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol, monohydrobromide. CAS Number: 108179-91-5. Molecular Formula: C17H18BrNO . HBr. Formula Weight: 413.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 100 mM, Ethanol: 25 mM, Water: 5 mM. SMILES: OC1=C(Br)C=C(CCN(C)CC2C3=CC=CC=C3)C2=C1.Br. InChi Code: InChI=1S/C17H18BrNO.BrH/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12,/h2-6,9-10,15,20H,7-8,11H2,1H3,1H. InChi Key: SDQJYYGODYRPBR-UHFFFAOYSA-N.